Best CBD Cream for Alzheimer’s and Dementia

Dementia is a medical condition characterized by a progressive decline in an individual's cognitive abilities, including memory and thinking skills. Alzheimer's disease, a common form of dementia, is associated with the gradual loss of brain cells and the accumulation of a protein called amyloid, which contributes to memory and cognitive impairment.

Both conditions primarily affect the brain and can lead to memory problems. Currently, there is no known cure for dementia or Alzheimer's disease, and preventive measures are limited. However, some treatments and interventions can help manage and alleviate certain symptoms.

CBD (cannabidiol) creams have gained attention for their potential therapeutic effects, but their role in managing dementia and Alzheimer's disease is not well-established. Some anecdotal reports suggest that CBD creams may help reduce behavioral symptoms such as aggression and agitation in individuals with dementia. These reports have sparked interest in CBD as a potential option for symptom management.

It's important to note that research on the use of CBD creams for dementia and Alzheimer's is limited, and their effectiveness and safety are not yet fully understood. Additionally, the exact causes of these conditions remain unknown.

As the number of Alzheimer's cases continues to rise, with approximately 5 million cases in the United States alone, there is growing interest in exploring potential treatments and interventions. While CBD creams have received positive feedback from some users, more research is needed to determine their efficacy and safety for dementia and Alzheimer's patients.

Selecting the right CBD cream can be challenging due to the variety of products available both online and in stores. It's crucial for individuals considering these products to seek guidance and consult with healthcare professionals when exploring potential treatment options.

In conclusion, while CBD creams may offer promise as a complementary approach to managing certain symptoms associated with dementia and Alzheimer's disease, further research is necessary to establish their effectiveness and safety. Patients and caregivers should approach such treatments with caution and seek professional advice when considering their use.

Our Overall #1 Rated Pick

  • Vegan 
  • Lab-tested
  • Third-party tested
  • 15% Discount and Free Shipping when you use the coupon code MEMORY.

Spruce CBD Topical Salve is a highly popular product in its range of CBD products. This salve is entirely natural and organic, crafted from straightforward ingredients. It's available in two concentrations: 1,000mg, which is over three times the dose found in our cream, and 2,000mg, boasting an impressive 6.7 times increase compared to Spruce CBD cream. 

The salve is easy to apply and free of petroleum products, making it ideal for patients with sensitivity to these ingredients. The smell is pleasant and mild, and application is easy. It contains full spectrum CBD oil, olive oil, shea butter, beeswax, and coconut oil, so it nourishes the skin while also helping alleviate symptoms.

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    Best CBD Cream for Alzheimer's and Dementia – Comparison Table

    Best CBD Cream for Alzheimer's and Dementia – Product Reviews

    In this section, we review the Top 10 CBD Cream for Alzheimer's and Dementia out there. Please note, presently, there is no scientific evidence to support the use of cannabidiol (CBD) products in treating or preventing the symptoms of Alzheimer's disease. Nonetheless, preliminary studies indicate that CBD may offer relief from certain symptoms associated with the condition.

    15% Discount and Free Shipping when you use the coupon code MEMORY.

    Alzheimer's is an undeniably devastating condition, capable of profoundly affecting one's life. As individuals age, the risk of developing dementia increases. Spruce Topical CBD Cream stands out as an exceptional CBD product designed to assist in managing pain and discomfort that may come about as a result of Alzheimer's and dementia.

    It works as an effective pain reliever for bumps, falls, minor injuries, or joint pain that can come with aging. This cream is formulated to be easy to apply and fast-acting. Effective pain relief can go a long way to creating a sense of calm and minimizing feelings of agitation and aggression.

    The product is all-natural and is suitable for vegans and those wanting gluten-free and non-GMO products.

    The high-quality full-spectrum CBD and hemp extract in this product work synergistically, swiftly absorbing into the skin to reduce inflammation and discomfort in affected areas.


    • Natural ingredients
    • Vegan-friendly
    • Lab and third-party tested
    • Made in the USA
    • Ships to all 50 states
    • GMO and gluten-free


    • It is not 100% THC free
    • People subject to drug testing should avoid this product as you may test positive
    • Contains citrus and coconut oil which can cause sensitivity in some
    • Bergamont can cause sun sensitivity on the skin

    15% Discount and Free Shipping when you use the coupon code MEMORY.

    The Spruce CBD Topical Salve is a highly sought-after product within the CBD product lineup. This salve is entirely natural and organic, made from simple and pure ingredients. It comes in two different concentrations: 1,000mg, which is more than three times the potency of our cream, and 2,000mg, boasting an impressive 6.7-fold increase compared to Spruce CBD cream.

    This salve is user-friendly and free from petroleum-based ingredients, making it an excellent choice for individuals with sensitivities to such components. It offers a pleasant and mild aroma, making the application process enjoyable. With ingredients like full-spectrum CBD oil, olive oil, shea butter, beeswax, and coconut oil, it not only soothes symptoms but also nourishes the skin.


    • Natural 
    • Non-GMO
    • Vegan 
    • Gluten-free 
    • Tested 
    • No artificial ingredients 
    • No pesticides


    • The coconut oil in the slave might trigger an allergy

    15% Discount and Free Shipping when you use the coupon code MEMORY.

    Spruce CBD cream is a natural option for those looking to manage Alzheimer's symptoms. This CBD lotion is formulated with a range of natural and vegan ingredients, including organic hemp extract carefully sourced from organic farms to ensure purity.

    When applied to the skin, the CBD oil extract facilitates rapid absorption into the bloodstream by opening nerve receptors. Rosemary, included in the lotion, serves as an anti-inflammatory and antioxidant.

    Eucalyptus oil is also present in sufficient quantities to promote skin healing, while aloe vera gel in the lotion maintains skin softness and moisture. The cream contains menthol extract, providing a cooling effect that can relax muscles and potentially enhance cognitive activity.

    It's important to note that while the cream contains some THC, the levels are lower than those found in comparable products. Consistent application is recommended, but it should be avoided during drug testing.

    Notably, the cream does not contain any artificial additives, scents, dyes, or chemicals, emphasizing its CBD-rich composition. To preserve its quality and freshness, it's advisable to store the lotion in a cool, shaded place away from direct sunlight, as heat and humidity can degrade the product.


    • Natural 
    • Tested 
    • Aloe Vera
    • Menthol 
    • Eucalyptus oil 
    • Rosemary 
    • No artificial additives 


    • It has coconut oil; you might be allergic 
    • It is not 100% THC-free; you might test positive for marijuana
    • Can interact with other medications; consult a healthcare provider

    Cheef Botanicals offers an affordable yet high-quality pure CBD cream. Alzheimer's is a complex cognitive disorder that affects older individuals and may lead to dementia symptoms. While there is no cure for this disease, some products have shown promise in managing its symptoms.

    Cheef Botanicals' CBD cream contains premium ingredients that work together effectively. With its high potency, it can help alleviate pain and other symptoms associated with Alzheimer's. The cream contains cannabinoids, which can positively impact cognitive function and sensory perception. Additionally, it provides moisturization for the skin, addressing dryness and other skin issues.

    One notable feature is that this cream undergoes rigorous lab testing for purity and safety, including third-party testing. It's essential to perform a patch test before using any new skincare product.


    • Natural ingredients 
    • Fast action 
    • Lab-tested 
    • Third-party tested 
    • Affordable 
    • Moisturize and calm 
    • An antioxidant like vitamin E


    • The 500mg may not be enough

    Nature's Best CBD cream is a topical solution known for its rapid and effective action. Alzheimer's is a severe disease that disrupts daily routines, primarily affecting older individuals who often experience dementia alongside it. It's crucial to address these conditions early to manage their progression.

    CBD creams like this one have shown promise in reducing memory loss and other long-term symptoms associated with Alzheimer's. This particular CBD cream stands out as it contains natural ingredients and is infused with full-spectrum CBD oil, ensuring quick results.

    While there's no cure for dementia, the primary goal of using a CBD cream is to alleviate the pain caused by Alzheimer's. This cream boasts high absorption rates, providing moisturization and soothing effects. Its standout features include being full spectrum, fast-acting, highly absorbent, moisturizing, and soothing.

    Nature's Best CBD cream is a leading product in the United States, known for its cannabinoid content. The hemp extract used in the cream is sourced from organic Hemp Farms, and the formula is designed for fast skin absorption. Importantly, the CBD is derived from hemp, not marijuana, and contains only 0.3% THC. While this THC amount is minimal and unlikely to produce psychoactive effects, it's advisable to check for allergies before use.


    • Organic ingredients 
    • Hemp extract
    • Cannabinoid 
    • Fact active 
    • Effective 
    • High absorption 
    • Tested


    • Not good if you are allergic to camphor or menthol 
    • If you are subject to a drug test, do not use it

    The CBDol Topical CBD cream offers remarkable potential at an affordable price point. Alzheimer's is an exceptionally severe and life-disrupting disorder often accompanied by dementia. It profoundly affects brain function, making it crucial to explore medications and supplements that can help mitigate its impact.

    Topical CBD creams are carefully formulated to provide relief and a sense of calm within your body. This particular cream is crafted from organically sourced hemp from farms, ensuring both fast-acting and enduring results. Its application is effortless, but it's essential to conduct a patch test beforehand to rule out any allergies.

    This topical CBD cream is non-GMO and contains oils extracted from the aerial parts of plants. Rigorous lab testing, including third-party assessments, guarantees its purity. The cream also possesses moisturizing properties, ensuring it won't harm your skin.

    All the ingredients used are organic and naturally extracted, making it an excellent choice for vegetarians. A standout feature of this CBD Cream is its ISO certification. To maintain its freshness and quality, it should be stored in a cool, dry, and shaded place. Even slight humidity or moisture can have a detrimental impact on its effectiveness.


    • Natural 
    • Non-GMO
    • ISO certified 
    • Soothing 
    • Fast action 
    • Lab-tested 
    • Third-party tested
    • Full-spectrum Cannabinoid


    • Not recommended if you are allergic to camphor 

    Joy Organics CBD cream is a premium, THC-free solution ideal for Alzheimer's and dementia. It offers fast absorption and soothing effects. Derived from organic hemp farms rich in cannabinoids, it promotes skin health, joint comfort, and softness. This multifunctional cream is vegan, lab, and third-party tested for purity, with results available online. Store it in a cool, dry place to maintain freshness.

    This product is an ideal solution for those wanting to avoid ingesting oil or tinctures. As a topical cream, it can be applied with pinpoint accuracy without needing to be metabolized by the body first. Being 100% THC-free, it's also safe for people requiring drug testing.


    • Natural 
    • Lab-tested 
    • Third-party tested 
    • THC free
    • Fast absorption 
    • Premium Grade
    • Promote healthy skin


    • The price can be a barrier 
    • Some people might be allergic to essential oils

    The Green Roads CBD cream upholds high-quality standards, adhering to cGMPs in production. It's a safe and effective option for managing Alzheimer's and dementia symptoms. The cream is consistent and side-effect-free, with lab and third-party testing ensuring purity.

    It contains all-natural, vegan, gluten-free ingredients and is cruelty-free. THC-free and with a mild scent, it soothes both body and mind. Store it in a cool, dry place for optimal freshness.

    Green Roads CBD cream comes in OTC strength, making it more effective than many options available online. There is 750mg of CBD per bottle, and ingredients like avocado oil, vitamin E, and cucumber offer nourishing and soothing skin support.



    • Organic 
    • Gluten-free 
    • THC free 
    • Vegan 
    • No artificial additives 
    • No Artificial flavors 
    • Natural oils 
    • Mild scent 
    • Heavy-metals testing 
    • Lab-tested 
    • Third-party tested 
    • Cruelty-free 


    • The price can be a barrier for larger quantities
    • Some ingredients can cause skin irritation or sensitivity for some

    Best CBD Cream for Alzheimer’s and Dementia - Buying Guide

    What is CBD?

    CBD, short for Cannabidiol, is indeed a compound naturally occurring in the buds of the cannabis plant. It's recognized for its potential anti-anxiety and pain-relieving properties. CBD's significance in these creams lies in its potential anti-inflammatory properties, which could aid in mitigating neurodegenerative symptoms in patients.

    Patients with Alzheimer's and certain forms of dementia often exhibit the accumulation of a protein known as Amyloid within nerve cells and tissues, believed by researchers to be a contributing factor to these conditions.

    While animal studies have suggested that CBD creams might protect against the aggregation of these proteins, it's important to note that concrete evidence of CBD creams reducing brain inflammation is still lacking.

    Let's delve into how CBD functions and explore essential considerations before purchasing such products.

    How does CBD Cream work?

    Several studies have explored the potential use of CBD in managing dementia. A 2017 study conducted in California suggested that CBD may help alleviate neurological symptoms associated with dementia and related conditions by facilitating the restoration of connections between previously affected brain cells.

    The mechanism of action of CBD creams involves reducing inflammation and promoting improved oxygen circulation within brain cells. These issues are commonly observed in dementia patients and have adverse effects on overall neurological function, contributing to cell death and disruptions in cellular connectivity.

    In Alzheimer's disease, an escalation in reactive and stress-induced oxygen is a primary contributor to the deterioration of brain cells and tissues. CBD, with its antioxidant properties, can facilitate the removal of excess oxygen from brain cells and stimulate the growth and development of brain cells.

    In this way, CBD creams may not only help alleviate symptoms but also contribute to the recovery process. The rejuvenation of connections between brain cells and the development of new cells can enhance memory and other cognitive functions.

    Structure and Composition

    As previously mentioned, CBD creams contain infused Cannabidiol as the active ingredient. Cannabidiol is one of nearly 114 compounds found in the hemp plant, which is distinct from marijuana and THC. While CBD and THC share the same molecular formula, their differing molecular structures grant them distinct properties, utilized in various medicinal and sedative applications.

    CBD is notably abundant in hemp plants, constituting nearly 40% of the total phytochemicals and other terpenes present in the plant. This high prevalence makes CBD relatively easier to extract in its pure form.

    The precise composition and all additional ingredients of CBD creams will be listed on the product packaging, and it is advisable to review this information before making a purchase.

    THC Levels

    THC, or tetrahydrocannabinol, is the compound responsible for the "high" sensation associated with cannabis. This compound has contributed to a negative perception of the cannabis plant and any products incorporating Cannabis compounds. Due to its potential for altering brain function, scientists have shown specific interest in its potential use as a sedative.

    THC has often received negative attention due to its potential for recreational use. It can make users more sensitive to external stimuli and less in control of their emotions. Despite this reputation, CBD creams may contain small quantities of THC to enhance the efficiency of Cannabidiol (CBD).

    The FDA deems amounts as low as 0.2-0.3% acceptable for legal use, as such minimal quantities do not induce any "high" or cognitive impairment effects. This usage, known as reinforcement use, aims to improve the efficacy of CBD without producing harmful effects.

    Full Spectrum CBD and Why to Opt for It

    There are specific labels on many CBD products, including "Full Spectrum CBD." Full-spectrum indicates that the product contains CBD along with various phytochemicals, such as essential terpenoids, phytonutrients, minor cannabinoids, and even traces of THC.

    These compounds from the hemp plant work together synergistically, enhancing the effectiveness of CBD. This combined action is known as the entourage effect, and it's why full-spectrum CBD products are often considered more beneficial than CBD isolates.

    Full-spectrum CBD may also contain traces of CBG, CBC, and CBN. CBN is known for its relaxing properties and is being studied as a potential sedative when used in higher doses. CBG, or Cannabigerol, is a non-intoxicating compound found in hemp plants and serves as a precursor to CBD. Adding CBG with specific enzymes can increase the CBD content in creams. These additional natural compounds from hemp plants make full-spectrum CBD creams more efficient and desirable than broad-spectrum alternatives.

    These creams, while offering numerous benefits, are derived from the Cannabis plant. Cannabis is known for its psychoactive effects primarily caused by the presence of the cannabinoid THC (Tetrahydrocannabinol).

    It's important to note that CBD (Cannabidiol) is the primary component of these creams, responsible for their therapeutic properties. CBD does not produce the "high" associated with THC. CBD has been found to be non-intoxicating and safe for use by people of all ages, including children and seniors. There is no risk of overdosing on CBD.

    CBD does not harm the neurological system or alter one's state of mind, meaning it doesn't induce a euphoric sensation. However, some individuals may experience mild digestive issues like diarrhea when using CBD. Additionally, CBD may interact with certain blood-thinning medications, so it's advisable to consult with a healthcare professional if you plan to use CBD creams while taking other medications.

    CBD Cream - Is It Legal?

    The legal status of cannabis and related products varies from state to state. While cannabis is prohibited in many states, some have legalized it. The key distinction lies in whether the cream contains hemp or marijuana.

    CBD creams can be formulated using either hemp or marijuana. Products made from hemp are generally more widely accepted in all 50 states. Hemp contains approximately 0.3% THC, which is within the legal and socially acceptable limit. It's important that the hemp used in these CBD creams is organic and domestically sourced.

    The DEA classifies cannabis as a Schedule 1 controlled substance, but despite this federal classification, many states have legalized cannabis in various forms. To ensure that CBD creams are legal and safe for use in your specific state, it is advisable to research and confirm your state's regulations.

    Although CBD creams may still face skepticism due to the stigma surrounding cannabis, their therapeutic benefits are increasingly recognized. To address concerns about legality, it's crucial to verify that the use of CBD creams is permitted and regulated within your state.

    Purity Levels 

    You might have come across CBD products labeled as "carbon dioxide" or "CO2 extracted." These labels are also common in dementia CBD creams. This designation indicates that carbon dioxide is used to extract and purify the plant before further processing.

    This method ensures the highest level of purity in the plant extract. The release and removal of pressurized carbon dioxide make for a straightforward and efficient extraction process, resulting in the isolation of desired and beneficial phytochemicals. These purified phytochemicals are then incorporated into CBD oil and creams to ensure the highest quality and effectiveness.

    While CO2 extraction is an excellent process for obtaining pure chemicals, it is both costly and requires a high level of expertise and skilled personnel. Consequently, products produced using this method may be more expensive compared to others. However, the investment in quality and purity is well worth it. When you see a label indicating CO2 extraction, it signifies that the company has prioritized product quality and efficacy, which may come at a slightly higher price point but offers efficient and reliable results.

    Side Effects and Other Risks

    According to the World Health Organization (WHO), there have been no severe cases reported related to the use of CBD creams. Instances of unhealthy dependence, misuse, or abuse of these creams have not been reported either.

    No deaths or dangerous situations have been associated with the use of CBD creams or oils, including among individuals with dementia or Alzheimer's. The most commonly reported side effects include diarrhea and bloating. A small fraction of users have also experienced nausea as a side effect. However, it's crucial to emphasize that overdose is strictly prohibited, as indicated on the product packaging.

    In some cases, users have reported increased body tremors due to overuse of CBD creams. Given that this product is relatively new, and its effects are still being studied, proper assessment and monitoring of patients should be conducted by caregivers to ensure that no new side effects arise.

    It's important to note that CBD may interact with other medications, which could pose potential risks, especially if the individual is also taking blood thinners. In such cases, it is strongly advisable to seek guidance from a healthcare professional.

    Liver issues have been reported in some cases due to interactions between CBD and certain medications. CBD can impact liver enzymes, either enhancing their function or interfering with the breakdown of medicinal compounds. This alteration in the metabolism of drugs can affect their normal functioning and potentially increase their toxicity in the body. Therefore, individuals using CBD in combination with other medications should be monitored by healthcare providers.

    Other Benefits

    Despite the negative stigma that has often surrounded the cannabis plant, it's essential to recognize its beneficial qualities and health benefits. CBD, in particular, has shown remarkable potential in providing relief from anxiety and depression.

    CBD offers a natural alternative to pharmaceutical medications, contributing to its growing popularity. Studies have indicated positive outcomes when CBD tablets are administered orally within specific dosage ranges.

    The mechanism of action for CBD involves binding to receptors on brain cells and facilitating the release of serotonin, which can help improve mood and induce relaxation. CBD is also utilized in pain-relieving medications and functions as a muscle relaxant.

    Both morphine and CBD share a common factor in their ability to relieve pain. They achieve this by interfering with the transmission of pain signals to the brain through nerve endings that connect the brain, spinal cord, and the affected area.

    Furthermore, CBD has demonstrated neuroprotective properties, making it a promising option for addressing neurological disorders such as epilepsy, Parkinson's disease, and dementia. While this field of research is relatively new and continues to evolve, the positive impact of CBD on these conditions cannot be dismissed.

    Look for the Source of Hemp

    When assessing CBD creams, it's essential to consider the source of the hemp used. The legality of hemp production hinges on specific conditions, including the requirement that hemp plants originate from domestically grown, purely organic cannabis plants.

    This practice ensures that the plants are safe, of high quality, and suitable for medicinal purposes. Hemp plants possess a unique characteristic known as hyperaccumulation, meaning they absorb and retain a wide range of nutrients and compounds from the soil.

    The organic cultivation of hemp plants in safe, quality soil is crucial to ensure that the plant material is safe and free from toxins, particularly when used in creams and oils.

    Frequently Asked Questions - FAQs

    How do you make sure that CBD cream is not contaminated with other chemicals?

    The easiest way to find that out is via the source label on the product. Most brands mention the source or plant that they extracted the product from. On the safe side, you can always look for those creams that have been tested by a third party. 

    CBD comes from a lot of plants, and source plants are easily and quite commonly mislabeled. When buying online, make sure the product is tested before and is 100% safe, and labeling is accurate.

    Is CBD a heavy sedative?

    Again, the stigma around the cannabis plant and its strains is coming into play. CBD is not a sedative. If anything, it makes the user more awake and aware. CBD has a relaxing effect, which is not to be confused with a sedative effect. 

    It shouldn’t make you feel any type of “high” or loss of control. What makes you feel “high” or used as a medical sedative is not CBD but other terpenes such as myrcene or THC.

    Is CBD psychoactive?

    Yes, CBD and CBD-based products are psychoactive. There are a lot of misconceptions about this particular point. Due to the antipsychotic and anti-anxiety effects of CBD, it is commonly thought to be non-psychoactive. 

    It’s just that the psychoactive effects that the CBD drug or cream brings about are beneficial and non-intoxicating. CBD also brings about a relaxing sensation but not to the point of a “high” feeling.

    Is CBD legal?

    In most states, yes. But it is better to make sure that your state or country allows product use. The actual plant may be illegal as Cannabis has a long history of being abused for recreational purposes. Other compounds are not allowed in a lot of countries due to their soothing nature and “high” effect.

    How does CBD work?

    CBD works by breaking down the proteinaceous compounds accumulated in the brain tissues. CBD also helps in activating receptors that are responsible for bringing more blood flow to the brain. This more blood flow helps in the rejuvenation of brain tissues that were affected due to protein accumulation.

    They also work by increasing brain activity and rekindling the connection between the brain and neurons.

    Best CBD cream for Alzheimer’s and Dementia – Final Word

    CBD is a relatively recent introduction to the medical field, but it has quickly gained recognition for its potential benefits. While dementia and Alzheimer's currently lack definitive cures or preventive treatments, CBD has shown promise in various medical applications, including pain relief, anxiety reduction, and potentially as an antidepressant.

    CBD's neuroprotective properties are also being explored, although further research is needed to ensure its safety in this regard. The positive outcomes associated with CBD have sparked increased interest among scientists and researchers, offering hope for further discoveries through ongoing studies.

    We trust that this guide has provided you with a better understanding of the concept and utilization of the best CBD creams for Alzheimer's and dementia. Armed with this knowledge, you can make more informed choices when selecting CBD creams.

    Here's to a happier, healthier you!